Title : Coupling of UDP-glucuronosyltransferases and multidrug resistance-associated proteins is responsible for the intestinal disposition and poor bioavailability of emodin.

Pub. Date : 2012 Dec 15

PMID : 22982073






1 Functional Relationships(s)
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1 MK-571, chemical inhibitor of MRP2, MRP3, and MRP4, significantly reduced the efflux of glucuronide in the apical-to-basolateral (A-B) and B-A directions in a dose-dependent manner. verlukast ATP binding cassette subfamily C member 2 Homo sapiens