Pub. Date : 2012
PMID : 22973984
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | P19 mouse embryonal carcinoma cells can differentiate into neurons when cultured in aggregates and induced with RA (retinoic acid). | Tretinoin | interleukin 23, alpha subunit p19 | Mus musculus |
| 2 | P19 mouse embryonal carcinoma cells can differentiate into neurons when cultured in aggregates and induced with RA (retinoic acid). | Tretinoin | interleukin 23, alpha subunit p19 | Mus musculus |
| 3 | P27KIP1 was up-regulated during the differentiation process of both P19/ADAM23KD cells without RA induction, and P19 cells with RA induction. | Tretinoin | interleukin 23, alpha subunit p19 | Mus musculus |
| 4 | The findings indicate that ADAM23 suppresses neuronal differentiation through its disintegrin domain, and Adam23 KD up-regulates P27KIP1 in P19/ADAM23KD cells, one reason that P19/ADAM23KD cells can differentiate into neurons without RA induction. | Tretinoin | interleukin 23, alpha subunit p19 | Mus musculus |
| 5 | The findings indicate that ADAM23 suppresses neuronal differentiation through its disintegrin domain, and Adam23 KD up-regulates P27KIP1 in P19/ADAM23KD cells, one reason that P19/ADAM23KD cells can differentiate into neurons without RA induction. | Tretinoin | interleukin 23, alpha subunit p19 | Mus musculus |