Pub. Date : 2012 Nov
PMID : 22972661
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The regulation of endogenous retinoic acid level through CYP26B1 is required for elevation of palatal shelves. | Tretinoin | cytochrome P450, family 26, subfamily b, polypeptide 1 | Mus musculus |
2 | In the present study, we deleted Cyp26b1, one of the RA-degrading enzymes, to further study the effects of excess RA in the normal developing palate and to understand how endogenous levels of RA are regulated. | Tretinoin | cytochrome P450, family 26, subfamily b, polypeptide 1 | Mus musculus |
3 | The regulation of RA signaling through CYP26B1 is also necessary for the development of tongue musculature and for tongue depression. | Tretinoin | cytochrome P450, family 26, subfamily b, polypeptide 1 | Mus musculus |