Pub. Date : 2013 Feb
PMID : 22966071
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Sterol regulatory element-binding protein-1c mediates increase of postprandial stearic acid, a potential target for improving insulin resistance, in hyperlipidemia. | stearic acid | insulin | Homo sapiens |
2 | The elevation of SA is due to increased insulin-stimulated de novo synthesis mediated by sterol regulatory element-binding protein-1c (SREBP-1c)/acetyl-CoA carboxylase/fatty acid synthase/elongation of long-chain fatty acid family member 6 (ELOVL6) and the elongation of palmitic acid (PA) catalyzed by ELOVL6. | stearic acid | insulin | Homo sapiens |
3 | In summary, increased postprandial SA is caused by the insulin-stimulated SREBP-1c pathway and elongation of PA in HLP. | stearic acid | insulin | Homo sapiens |