Title : Excision of 5-hydroxymethyluracil and 5-carboxylcytosine by the thymine DNA glycosylase domain: its structural basis and implications for active DNA demethylation.

Pub. Date : 2012 Nov 1

PMID : 22962365






1 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 TDG flips the target nucleotide from the double-stranded DNA, cleaves the N-glycosidic bond and leaves the C1" hydrolyzed abasic sugar in the flipped state. Sugars thymine DNA glycosylase Homo sapiens