Title : Excision of 5-hydroxymethyluracil and 5-carboxylcytosine by the thymine DNA glycosylase domain: its structural basis and implications for active DNA demethylation.

Pub. Date : 2012 Nov 1

PMID : 22962365






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 TDG allows hydrogen-bonding interactions to both T/U-based (5hmU) and C-based (5caC) modifications, thus enabling its activity on a wider range of substrates. Hydrogen thymine DNA glycosylase Homo sapiens