Pub. Date : 2012 Oct
PMID : 22953992
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Recently, our group showed that AMP-activated protein kinase (AMPK) plays a pivotal role in the rat thyroid gland, downregulating iodide uptake by thyroid cells even in the presence of its main stimulator thyrotropin (TSH). | Iodides | protein kinase AMP-activated catalytic subunit alpha 2 | Rattus norvegicus |
| 2 | Recently, our group showed that AMP-activated protein kinase (AMPK) plays a pivotal role in the rat thyroid gland, downregulating iodide uptake by thyroid cells even in the presence of its main stimulator thyrotropin (TSH). | Iodides | protein kinase AMP-activated catalytic subunit alpha 2 | Rattus norvegicus |
| 3 | Since AMPK increases glucose uptake in different tissues, and taken into consideration that in pathophysiological conditions such as thyroid cancer a negative correlation between iodide and glucose uptake occurs, we hypothesized that AMPK might modulate glucose uptake in thyroid cells. | Iodides | protein kinase AMP-activated catalytic subunit alpha 2 | Rattus norvegicus |
| 4 | Since AMPK increases glucose uptake in different tissues, and taken into consideration that in pathophysiological conditions such as thyroid cancer a negative correlation between iodide and glucose uptake occurs, we hypothesized that AMPK might modulate glucose uptake in thyroid cells. | Iodides | protein kinase AMP-activated catalytic subunit alpha 2 | Rattus norvegicus |