Title : Cortactin as a target for FAK in the regulation of focal adhesion dynamics.

Pub. Date : 2012

PMID : 22952866






4 Functional Relationships(s)
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1 PRINCIPAL FINDINGS: Using FAK-null fibroblasts stably reconstituted with green fluorescent protein (GFP) tagged FAK constructs, we find that FAK activity and FAK C-terminal proline-rich region 2 (PRR2) and PRR3 are required for FA turnover and cell motility. Proline protein tyrosine kinase 2 Homo sapiens
2 PRINCIPAL FINDINGS: Using FAK-null fibroblasts stably reconstituted with green fluorescent protein (GFP) tagged FAK constructs, we find that FAK activity and FAK C-terminal proline-rich region 2 (PRR2) and PRR3 are required for FA turnover and cell motility. Proline protein tyrosine kinase 2 Homo sapiens
3 PRINCIPAL FINDINGS: Using FAK-null fibroblasts stably reconstituted with green fluorescent protein (GFP) tagged FAK constructs, we find that FAK activity and FAK C-terminal proline-rich region 2 (PRR2) and PRR3 are required for FA turnover and cell motility. Proline protein tyrosine kinase 2 Homo sapiens
4 PRINCIPAL FINDINGS: Using FAK-null fibroblasts stably reconstituted with green fluorescent protein (GFP) tagged FAK constructs, we find that FAK activity and FAK C-terminal proline-rich region 2 (PRR2) and PRR3 are required for FA turnover and cell motility. Proline protein tyrosine kinase 2 Homo sapiens