Title : Therapeutic effects of quetiapine on memory deficit and brain β-amyloid plaque pathology in a transgenic mouse model of Alzheimer's disease.

Pub. Date : 2013 Mar

PMID : 22950911






2 Functional Relationships(s)
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1 After 8 months of continuous quetiapine administration, memory deficit was reversed and brain Abeta plaque pathology was attenuated in the AD mice. Quetiapine Fumarate amyloid beta (A4) precursor protein Mus musculus
2 Quetiapine also decreased the soluble Abeta peptide levels in brain and cerebrospinal fluid (CSF), and attenuated the decreased synaptic protein levels in the AD mice. Quetiapine Fumarate amyloid beta (A4) precursor protein Mus musculus