Title : Arsenic trioxide inhibits cell growth and induces apoptosis through inactivation of notch signaling pathway in breast cancer.

Pub. Date : 2012

PMID : 22949821






1 Functional Relationships(s)
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1 Taken together, our findings provide evidence showing that the down-regulation of Notch-1 by arsenic trioxide could be an effective approach, to cause down-regulation of Bcl-2, and NF-kappaB, resulting in the inhibition of cell growth and invasion as well as induction of apoptosis. Arsenic Trioxide nuclear factor kappa B subunit 1 Homo sapiens