Title : Identification of retinol binding protein 1 promoter hypermethylation in isocitrate dehydrogenase 1 and 2 mutant gliomas.

Pub. Date : 2012 Oct 3

PMID : 22945948






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 RBP1, important in retinoic acid metabolism, was found to be hypermethylated in 76 of 79 IDH1 MUT, 3 of 3 IDH2 MUT, and 0 of 116 IDH1/IDH2 WT tumors. Tretinoin retinol binding protein 1 Homo sapiens
2 Because RBP1 is involved in retinoic acid synthesis, our results suggest that dysregulation of retinoic acid metabolism may contribute to glioma formation along the IDH1/IDH2-mutant pathway. Tretinoin retinol binding protein 1 Homo sapiens
3 Because RBP1 is involved in retinoic acid synthesis, our results suggest that dysregulation of retinoic acid metabolism may contribute to glioma formation along the IDH1/IDH2-mutant pathway. Tretinoin retinol binding protein 1 Homo sapiens