Title : Review of evidence that epidemics of type 1 diabetes and type 2 diabetes/metabolic syndrome are polar opposite responses to iatrogenic inflammation.

Pub. Date : 2012 Nov

PMID : 22934546






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Finally, there is a strong mechanism data that macrophage produced interleukin 1, tumor necrosis factor and interleukin 6, which are released following inflammation, causing destruction of insulin secreting islet cells and increase cortisol release, and thus have the ability to cause both type 1 and type 2 diabetes/metabolic syndrome (which resembles a Cushingoid state). Hydrocortisone interleukin 1 alpha Homo sapiens