Title : The C5a receptor antagonist PMX205 ameliorates experimentally induced colitis associated with increased IL-4 and IL-10.

Pub. Date : 2013 Jan

PMID : 22924972






1 Functional Relationships(s)
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1 The purpose of this study was to further build on this evidence by examining the efficacy, mechanism and specificity of a potent, non-competitive and orally active C5a receptor (CD88) antagonist, PMX205, in the dextran sulphate sodium (DSS) model of murine innate colitis. dextran sulphate sodium complement component 5a receptor 1 Mus musculus