Title : SUMO modification of Stra13 is required for repression of cyclin D1 expression and cellular growth arrest.

Pub. Date : 2012

PMID : 22905217






1 Functional Relationships(s)
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1 Mutation of SUMO acceptor lysines 159 and 279 located in the C-terminal repression domain has no impact on nuclear localization; however, it abrogates association with the co-repressor histone deacetylase 1 (HDAC1), attenuates repression of cyclin D1, and prevents Stra13-mediated growth suppression. Lysine cyclin D1 Homo sapiens