Title : Re-induction of cell differentiation and (131)I uptake in dedifferentiated FTC-133 cell line by TSHR gene transfection.

Pub. Date : 2012 Nov

PMID : 22898315






2 Functional Relationships(s)
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1 This study aimed to test the therapeutic potential of TSHR in dedifferentiated DTC by gene transfection in order to restore cell differentiation and radioiodine uptake. Iodine-131 thyroid stimulating hormone receptor Homo sapiens
2 RESULTS: Among the thyroid specific genes in dFTC-133 cells with stable low radioiodine uptake, TSHR was down-regulated most significantly compared with FTC-133. Iodine-131 thyroid stimulating hormone receptor Homo sapiens