Title : Targeted tumor therapy with a fusion protein of an antiangiogenic human recombinant scFv and yeast cytosine deaminase.

Pub. Date : 2012 Sep

PMID : 22892453






1 Functional Relationships(s)
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1 We designed a fusion protein termed L19CDy-His, consisting of the antibody single chain fragment L19 for targeting ED-B and yeast cytosine deaminase for the conversion of 5-fluorocytosine into cytotoxic 5-fluorouracil. Flucytosine cytosine deaminase Saccharomyces cerevisiae S288C