Title : Molecular target validation, antimicrobial delivery, and potential treatment of Toxoplasma gondii infections.

Pub. Date : 2012 Aug 28

PMID : 22891343






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 PPMO directed against T. gondii"s dihydrofolate reductase (DHFR), an enzyme necessary for folate synthesis, limited tachyzoite replication. Folic Acid dihydrofolate reductase Mus musculus
2 Rescue with exogenous folate demonstrated DHFR PPMO"s specificity. Folic Acid dihydrofolate reductase Mus musculus