Title : Serotonin 1A receptor agonist increases species- and region-selective adult CNS proliferation, but not through CNTF.

Pub. Date : 2012 Dec

PMID : 22884499






2 Functional Relationships(s)
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1 Like others, we show that systemic treatment with the active R-enantiomer of the 5-HT1A agonist 8-Hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT)(5) induces proliferation in the SGZ in rats using unbiased stereology of 5-Bromo-2"-deoxyuridine (BrdU)(6) positive nuclei. 8-Hydroxy-2-(di-n-propylamino)tetralin 5-hydroxytryptamine receptor 1A Rattus norvegicus
2 Like others, we show that systemic treatment with the active R-enantiomer of the 5-HT1A agonist 8-Hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT)(5) induces proliferation in the SGZ in rats using unbiased stereology of 5-Bromo-2"-deoxyuridine (BrdU)(6) positive nuclei. 8-Hydroxy-2-(di-n-propylamino)tetralin 5-hydroxytryptamine receptor 1A Rattus norvegicus