Pub. Date : 2012 Aug
PMID : 22868769
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The 1.5 A resolution crystal structure of a complex between the SH3 domain of the Fyn tyrosine kinase and the C-terminal proline-rich motif of the NS5A-derived peptide APPIPPPRRKR has been solved. | Proline | FYN proto-oncogene, Src family tyrosine kinase | Homo sapiens |
| 2 | The proline-rich motif present in the NS5A protein seems to be important for RNA replication and virus assembly, and the promiscuous interaction of the Fyn SH3 domain with the NS5A C-terminal proline-rich peptide found in this crystallographic structure may be important in the virus infection cycle. | Proline | FYN proto-oncogene, Src family tyrosine kinase | Homo sapiens |
| 3 | The proline-rich motif present in the NS5A protein seems to be important for RNA replication and virus assembly, and the promiscuous interaction of the Fyn SH3 domain with the NS5A C-terminal proline-rich peptide found in this crystallographic structure may be important in the virus infection cycle. | Proline | FYN proto-oncogene, Src family tyrosine kinase | Homo sapiens |