Title : Expression of human CYP27B1 in Escherichia coli and characterization in phospholipid vesicles.

Pub. Date : 2012 Oct

PMID : 22862690






1 Functional Relationships(s)
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1 Human CYP27B1 was also active on 25-hydroxyvitamin D(2) and on intermediates of the CYP24A1-mediated inactivation pathway, 24R,25-dihydroxyvitamin D3, 24-oxo-25-hydroxyvitamin D3 and 24-oxo-23,25-dihydroxyvitamin D3, with all these substrates showing comparable k(cat) values of 50-71 min(-1) , similar to 25-hydroxyvitamin D3. Calcifediol cytochrome P450 family 24 subfamily A member 1 Homo sapiens