Pub. Date : 2012 Oct 1
PMID : 22850421
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Conversely, prostate cancer cells, upon contact with CAFs, were reprogrammed toward aerobic metabolism, with a decrease in GLUT1 expression and an increase in lactate upload via the lactate transporter MCT1. | Lactic Acid | solute carrier family 16 member 1 | Homo sapiens |
| 2 | In agreement, pharmacologic inhibition of MCT1-mediated lactate upload dramatically affected prostate cancer cell survival and tumor outgrowth. | Lactic Acid | solute carrier family 16 member 1 | Homo sapiens |