Title : Cysteinyl leukotriene signaling aggravates myocardial hypoxia in experimental atherosclerotic heart disease.

Pub. Date : 2012

PMID : 22848603






1 Functional Relationships(s)
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1 In human heart biopsies from 14 patients with chronic coronary artery disease mRNA expression levels of LTC(4)S and CysLT1 were increased in chronic ischemic compared to non-ischemic myocardium, constituting a molecular basis for increased cys-LT signaling. Cysteine leukotriene C4 synthase Homo sapiens