Pub. Date : 2012 Oct 1
PMID : 22842334
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Novel bis-(-)-nor-meptazinol derivatives act as dual binding site AChE inhibitors with metal-complexing property. | Metals | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 2 | In the present study, two derivatives (ZLA and ZLB) of a potent dual binding site AChE inhibitor bis-(-)-nor-meptazinol (bis-MEP) were designed and synthesized by introducing metal chelating pharmacophores into the middle chain of bis-MEP. | Metals | acetylcholinesterase (Cartwright blood group) | Homo sapiens |