Title : Gene expression signatures associated with the in vitro resistance to two tyrosine kinase inhibitors, nilotinib and imatinib.

Pub. Date : 2011 Aug

PMID : 22829191






1 Functional Relationships(s)
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1 Upregulation of EGF and JAG1 oncogenes as well as genes encoding ATP-dependent drug efflux pump proteins such as ABCB1 was also observed in the resistant cells, which may confer alternative survival benefits. Adenosine Triphosphate ATP binding cassette subfamily B member 1 Homo sapiens