Title : Activation-induced cytidine deaminase-initiated off-target DNA breaks are detected and resolved during S phase.

Pub. Date : 2012 Sep 1

PMID : 22826323






2 Functional Relationships(s)
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1 Our results reveal novel cell cycle dynamics in response to AID-initiated DSBs, and suggest that the regulation of the repair of these DSBs through the cell cycle may ensure proper class switching while preventing AID-induced genomic instability. dsbs activation induced cytidine deaminase Homo sapiens
2 Our results reveal novel cell cycle dynamics in response to AID-initiated DSBs, and suggest that the regulation of the repair of these DSBs through the cell cycle may ensure proper class switching while preventing AID-induced genomic instability. dsbs activation induced cytidine deaminase Homo sapiens