Title : Cyclooxygenase-2, not microsomal prostaglandin E synthase-1, is the mechanism for interleukin-1β-induced prostaglandin E2 production and inhibition of insulin secretion in pancreatic islets.

Pub. Date : 2012 Sep 14

PMID : 22822059






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Arachidonic acid is converted to prostaglandin E(2) (PGE(2)) by a sequential enzymatic reaction performed by two isoenzyme groups, cyclooxygenases (COX-1 and COX-2) and terminal prostaglandin E synthases (cPGES, mPGES-1, and mPGES-2). Prostaglandins E mitochondrially encoded cytochrome c oxidase II Homo sapiens