Title : The emerging role of human esterases.

Pub. Date : 2012

PMID : 22813719






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Arylacetamide deacetylase (AADAC) is involved in the hydrolysis of flutamide, phenacetin, and rifamycins. Phenacetin arylacetamide deacetylase Homo sapiens
2 Arylacetamide deacetylase (AADAC) is involved in the hydrolysis of flutamide, phenacetin, and rifamycins. Phenacetin arylacetamide deacetylase Homo sapiens
3 AADAC is associated with adverse drug reactions because the hydrolytic metabolites of flutamide and phenacetin appear to be associated with hepatotoxicity and nephrotoxicity/hematotoxicity, respectively. Phenacetin arylacetamide deacetylase Homo sapiens