Title : Fucosyltransferase IV enhances expression of MMP-12 stimulated by EGF via the ERK1/2, p38 and NF-κB pathways in A431 cells.

Pub. Date : 2012

PMID : 22799384






2 Functional Relationships(s)
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1 In addition, ERK1/2 and p38 MAPK were shown to play a crucial role in mediating EGF-induced NF-kappaB translocation and phosphorylation of IkappaBalpha when treated with the MAPK inhibitors, PD98059 and SB203580, which resulted in increased MMP-12 expression. SB 203580 mitogen-activated protein kinase 3 Homo sapiens
2 In addition, ERK1/2 and p38 MAPK were shown to play a crucial role in mediating EGF-induced NF-kappaB translocation and phosphorylation of IkappaBalpha when treated with the MAPK inhibitors, PD98059 and SB203580, which resulted in increased MMP-12 expression. SB 203580 mitogen-activated protein kinase 3 Homo sapiens