Title : Efficient deamination of 5-methylcytosines in DNA by human APOBEC3A, but not by AID or APOBEC3G.

Pub. Date : 2012 Oct

PMID : 22798497






5 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 This is based in part on reported ability of activation-induced deaminase (AID) to deaminate 5-methylcytosines (5mC) to thymine. 5-Methylcytosine activation induced cytidine deaminase Homo sapiens
2 This is based in part on reported ability of activation-induced deaminase (AID) to deaminate 5-methylcytosines (5mC) to thymine. 5-Methylcytosine activation induced cytidine deaminase Homo sapiens
3 This is based in part on reported ability of activation-induced deaminase (AID) to deaminate 5-methylcytosines (5mC) to thymine. 5-Methylcytosine activation induced cytidine deaminase Homo sapiens
4 This is based in part on reported ability of activation-induced deaminase (AID) to deaminate 5-methylcytosines (5mC) to thymine. 5-Methylcytosine activation induced cytidine deaminase Homo sapiens
5 When the DNA-binding segment of AID was replaced with the corresponding segment from APOBEC3A, the resulting hybrid had much higher ability to convert 5mC to T in the genetic assay. 5-Methylcytosine activation induced cytidine deaminase Homo sapiens