Title : Hydrogen peroxide attenuates the prosurvival signaling of insulin-like growth factor-1 through two pathways.

Pub. Date : 2012 Sep 12

PMID : 22797316






4 Functional Relationships(s)
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1 Hydrogen peroxide attenuates the prosurvival signaling of insulin-like growth factor-1 through two pathways. Hydrogen Peroxide insulin like growth factor 1 Homo sapiens
2 In this study, we found that the prosurvival signaling of IGF-1 was attenuated by H2O2. Hydrogen Peroxide insulin like growth factor 1 Homo sapiens
3 IGF-1 exerted a potent neuroprotective effect against B27 deprivation, and this effect was abolished by 100 muM H2O2. Hydrogen Peroxide insulin like growth factor 1 Homo sapiens
4 These results showed that H2O2 impaired IGF-1 prosurvival signaling through two pathways. Hydrogen Peroxide insulin like growth factor 1 Homo sapiens