Title : Temporally designed treatment of melanoma cells by ATRA and polyI: C results in enhanced chemokine and IFNβ secretion controlled differently by TLR3 and MDA5.

Pub. Date : 2012 Oct

PMID : 22797253






1 Functional Relationships(s)
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1 In conclusion, consecutive treatment with ATRA and polyI:C results in strong, TLR3/MDA5-mediated chemokine and IFN responses in cultured human melanoma cells, which triggers a functional migratory response in professional antigen-presenting cells. Tretinoin interferon alpha 1 Homo sapiens