Pub. Date : 2012 Sep 1
PMID : 22796327
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | A significant increase in Akt activation was observed in proline-treated cells after hydrogen peroxide stress along with a corresponding increase in the phosphorylation of the forkhead transcription factor class O3a (FoxO3a). | Proline | AKT serine/threonine kinase 1 | Homo sapiens |
2 | The results provide evidence that PRODH is essential in proline protection against hydrogen peroxide-mediated cell death and that proline/PRODH helps activate Akt in cancer cells. | Proline | AKT serine/threonine kinase 1 | Homo sapiens |