Pub. Date : 2012 Sep 1
PMID : 22796327
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Proline dehydrogenase is essential for proline protection against hydrogen peroxide-induced cell death. | Hydrogen Peroxide | proline dehydrogenase 1 | Homo sapiens |
| 2 | Knockdown of PRODH in PC3 cells attenuated phosphorylated levels of Akt and FoxO3a and decreased cell survival during hydrogen peroxide stress. | Hydrogen Peroxide | proline dehydrogenase 1 | Homo sapiens |
| 3 | The results provide evidence that PRODH is essential in proline protection against hydrogen peroxide-mediated cell death and that proline/PRODH helps activate Akt in cancer cells. | Hydrogen Peroxide | proline dehydrogenase 1 | Homo sapiens |