Title : Indole based cyclooxygenase inhibitors: synthesis, biological evaluation, docking and NMR screening.

Pub. Date : 2012 Aug

PMID : 22796043






1 Functional Relationships(s)
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1 Accordingly, indole positions C-5, C-3 and N-1 were substituted with: sulfonamide or methylsulfone at C-5, p-halo-benzyl group at C-3, and an alkyl chain with a trifluoromethyl group at N-1. Sulfonamides complement C3 Homo sapiens