Title : Plant natural compounds: targeting pathways of autophagy as anti-cancer therapeutic agents.

Pub. Date : 2012 Oct

PMID : 22765290






1 Functional Relationships(s)
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1 In this review, we focus on highlighting several representative plant natural compounds such as curcumin, resveratrol, paclitaxel, oridonin, quercetin and plant lectin - that may lead to cancer cell death - for regulation of some core autophagic pathways, involved in Ras-Raf signalling, Beclin-1 interactome, BCR-ABL, PI3KCI/Akt/mTOR, FOXO1 signalling and p53. Quercetin tumor protein p53 Homo sapiens