Pub. Date : 2012
PMID : 22761954
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | METHODOLOGY/PRINCIPAL FINDINGS: Using flow cytometric analysis of cells labeled with cyclin A, annexin V and propidium iodide, we describe a time and dose-dependent arrest of the cell cycle in G0/G1 phase of the cell cycle and apoptosis following extract treatment in MCF-7 (WT-p53) and MDA-MB-231 (mutant-p53) human breast cancer cell lines with a markedly reduced effect on primary human mammary epithelial cells. | Propidium | tumor protein p53 | Homo sapiens |
2 | METHODOLOGY/PRINCIPAL FINDINGS: Using flow cytometric analysis of cells labeled with cyclin A, annexin V and propidium iodide, we describe a time and dose-dependent arrest of the cell cycle in G0/G1 phase of the cell cycle and apoptosis following extract treatment in MCF-7 (WT-p53) and MDA-MB-231 (mutant-p53) human breast cancer cell lines with a markedly reduced effect on primary human mammary epithelial cells. | Propidium | tumor protein p53 | Homo sapiens |