Title : The importance of LDL and cholesterol metabolism for prostate epithelial cell growth.

Pub. Date : 2012

PMID : 22761797






1 Functional Relationships(s)
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1 Treatment with cholesterol-lowering simvastatin induced up to 90% reduction in relative cell number of normal cell lines but a 15-20% reduction in relative number of cancer cells, an effect accompanied by sharp upregulation of HMGCR and LDLR. Simvastatin low density lipoprotein receptor Homo sapiens