Title : Overcoming multidrug-resistance in vitro and in vivo using the novel P-glycoprotein inhibitor 1416.

Pub. Date : 2012 Dec

PMID : 22757751






1 Functional Relationships(s)
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Protein Name
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1 1416 significantly enhanced cytotoxicity of VBL (vinblastine) in P-gp-overexpressed human multidrug-resistant K562/ADM (adriamycin) and KBV cells, but had no such effect on the parent K562 and KB cells. Vinblastine ATP binding cassette subfamily B member 1 Homo sapiens