Title : Lack of Ach1 CoA-Transferase Triggers Apoptosis and Decreases Chronological Lifespan in Yeast.

Pub. Date : 2012

PMID : 22754872






1 Functional Relationships(s)
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1 On the whole, our data provide further evidence of the role of acetic acid as cell-extrinsic mediator of cell death during chronological aging and highlight a primary role of Ach1 enzymatic activity in acetic acid detoxification which is important for mitochondrial functionality. Acetic Acid acetyl-CoA hydrolase Saccharomyces cerevisiae S288C