Pub. Date : 2012 Aug 10
PMID : 22749528
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We demonstrate that glutamine in combination with leucine activates mammalian TORC1 (mTORC1) by enhancing glutaminolysis and alpha-ketoglutarate production. | Leucine | CREB regulated transcription coactivator 1 | Mus musculus |
| 2 | Thus, mTORC1 senses and is activated by glutamine and leucine via glutaminolysis and alpha-ketoglutarate production upstream of Rag. | Leucine | CREB regulated transcription coactivator 1 | Mus musculus |