Title : Mechanisms of tetrandrine and 5-bromotetrandrine in reversing multidrug resistance may relate to down-regulation of multidrug resistance associated protein 7 expression.

Pub. Date : 2012 Jun

PMID : 22739155






5 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Both tetrandrine (Tet) and 5-bromotetrandrine (BrTet) can effectively reverse P-glycoprotein (P-gp)-mediated multidrug resistance (MDR). tetrandrine ATP binding cassette subfamily B member 1 Homo sapiens
2 Both tetrandrine (Tet) and 5-bromotetrandrine (BrTet) can effectively reverse P-glycoprotein (P-gp)-mediated multidrug resistance (MDR). tetrandrine ATP binding cassette subfamily B member 1 Homo sapiens
3 Both tetrandrine (Tet) and 5-bromotetrandrine (BrTet) can effectively reverse P-glycoprotein (P-gp)-mediated multidrug resistance (MDR). tetrandrine ATP binding cassette subfamily B member 1 Homo sapiens
4 Both tetrandrine (Tet) and 5-bromotetrandrine (BrTet) can effectively reverse P-glycoprotein (P-gp)-mediated multidrug resistance (MDR). tetrandrine ATP binding cassette subfamily B member 1 Homo sapiens
5 The protein level of P-gp decreased by 58.47% and 52.20% in the 1 micromol/L Tet and 2 micromol/L BrTet groups. tetrandrine ATP binding cassette subfamily B member 1 Homo sapiens