Title : Protein kinase C stimulates HuD-mediated mRNA stability and protein expression of neurotrophic factors and enhances dendritic maturation of hippocampal neurons in culture.

Pub. Date : 2012 Dec

PMID : 22736542






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Bryostatin, a PKC activator, treatment enhanced their association with HuD and increased these transcripts" stability. Bryostatins proline rich transmembrane protein 2 Homo sapiens
2 Bryostatin induced HuD phosphorylation, which was inhibited by Ro 32-0432, a specific PKC inhibitor. Bryostatins proline rich transmembrane protein 2 Homo sapiens
3 Furthermore cotreatment of bryostatin and AMI-1, a specific CARM1 inhibitor, potentiated PKC-dependent HuD-mRNA interactions and enhanced dendritic arborization. Bryostatins proline rich transmembrane protein 2 Homo sapiens