Pub. Date : 2012 Aug 1
PMID : 22734631
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | An expeditious synthesis of the MDM2-p53 inhibitor AM-8553. | 2-(5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(2-hydroxypentan-3-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid | tumor protein p53 | Homo sapiens |
| 2 | The development of the structurally complex MDM2/p53 inhibitor AM-8553 was impeded by the low yield of the initial synthesis. | 2-(5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(2-hydroxypentan-3-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid | tumor protein p53 | Homo sapiens |