Title : Sodium phenylbutyrate controls neuroinflammatory and antioxidant activities and protects dopaminergic neurons in mouse models of Parkinson's disease.

Pub. Date : 2012

PMID : 22723850






2 Functional Relationships(s)
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1 Here we demonstrate that sodium phenylbutyrate (NaPB), an FDA-approved therapy for reducing plasma ammonia and glutamine in urea cycle disorders, can suppress both proinflammatory molecules and reactive oxygen species (ROS) in activated glial cells. Reactive Oxygen Species N-ethylmaleimide sensitive fusion protein attachment protein beta Mus musculus
2 Here we demonstrate that sodium phenylbutyrate (NaPB), an FDA-approved therapy for reducing plasma ammonia and glutamine in urea cycle disorders, can suppress both proinflammatory molecules and reactive oxygen species (ROS) in activated glial cells. Reactive Oxygen Species N-ethylmaleimide sensitive fusion protein attachment protein beta Mus musculus