Title : Butein inhibits ethanol-induced activation of liver stellate cells through TGF-β, NFκB, p38, and JNK signaling pathways and inhibition of oxidative stress.

Pub. Date : 2013 Feb

PMID : 22722906






2 Functional Relationships(s)
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1 Butein inhibits ethanol-induced activation of liver stellate cells through TGF-beta, NFkappaB, p38, and JNK signaling pathways and inhibition of oxidative stress. Ethanol mitogen-activated protein kinase 8 Homo sapiens
2 In ethanol-induced HSCs, butein inhibited the activation of the p38 MAPK and JNK transduction pathways as well as significantly inhibiting the phosphorylation of NF kappaB inhibitor (IkappaB) and Smad3. Ethanol mitogen-activated protein kinase 8 Homo sapiens