Pub. Date : 2012
PMID : 22720080
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Fangchinoline inhibits human immunodeficiency virus type 1 replication by interfering with gp160 proteolytic processing. | fangchinoline | Envelope surface glycoprotein gp160, precursor | Human immunodeficiency virus 1 |
| 2 | Western blot analysis of HIV envelope proteins expressed in transfected 293T cells and in isolated virions showed that fangchinoline inhibited HIV-1 gp160 processing, resulting in reduced envelope glycoprotein incorporation into nascent virions. | fangchinoline | Envelope surface glycoprotein gp160, precursor | Human immunodeficiency virus 1 |
| 3 | Collectively, our results demonstrate that fangchinoline inhibits HIV-1 replication by interfering with gp160 proteolytic processing. | fangchinoline | Envelope surface glycoprotein gp160, precursor | Human immunodeficiency virus 1 |