Title : Over-sulfated chondroitin sulfate derivatives induce osteogenic differentiation of hMSC independent of BMP-2 and TGF-β1 signalling.

Pub. Date : 2013 Feb

PMID : 22718137






1 Functional Relationships(s)
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1 These data suggest that over-sulfated CS derivatives themselves are able to induce osteogenic differentiation, probably independent of BMP-2 and TGF-beta1 signalling, and offer therefore an interesting approach for the improvement of bone healing. Chondroitin Sulfates transforming growth factor beta 1 Homo sapiens