Title : The let-7 microRNA enhances heme oxygenase-1 by suppressing Bach1 and attenuates oxidant injury in human hepatocytes.

Pub. Date : 2012 Nov-Dec

PMID : 22698995






1 Functional Relationships(s)
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1 Furthermore, Huh-7 cells transfected with let-7b, let-7c or miR-98 mimic showed increased resistance against oxidant injury induced by tert-butyl-hydroperoxide (tBuOOH), whereas the protection was abrogated by over-expression of Bach1. tert-Butylhydroperoxide microRNA let-7b Homo sapiens