Pub. Date : 2012 Aug
PMID : 22692797
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | By first comparing how 39 amino acid substitutions throughout hSOD1 affected SDS-PAGE migration, we found that substitutions that caused gel shifting occurred within a single polyacidic domain (residues ~80-101), and were nonisoelectric. | Sodium Dodecyl Sulfate | superoxide dismutase 1 | Homo sapiens |
| 2 | Capillary electrophoresis, circular dichroism, and size exclusion chromatography demonstrated that amino acid substitutions increase migration during SDS-PAGE by promoting the binding of three to four additional SDS molecules, without significantly altering the secondary structure or Stokes radius of hSOD1-SDS complexes. | Sodium Dodecyl Sulfate | superoxide dismutase 1 | Homo sapiens |