Title : Metyrapone: a management option for ectopic ACTH syndrome in small cell lung cancer treated with intravenous etoposide.

Pub. Date : 2011 Aug 4

PMID : 22687664






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Etoposide is metabolised by cytochrome P450 3A4. Etoposide cytochrome P450 family 3 subfamily A member 4 Homo sapiens
2 There is an additional increased risk of toxicity due to a potential interaction between etoposide and ketoconazole, which is a strong inhibitor of cytochrome P450 3A4, and theoretically can lead to greater myelosuppression. Etoposide cytochrome P450 family 3 subfamily A member 4 Homo sapiens